Dr. Pathik Parikh Hepatologist and Liver Transplant Physician

  Liver as you all know it, is not only the second largest organ of the body after skin, but also a major organ for metabolizing. Whatever we eat goes to liver before reaching anywhere else in the body. The liver stores the excess energy as fat and condensed glucose known as glycogen. So whenever we eat excessively, the energy is stored in liver as fat. If we continue to do so for months and years together, the liver starts accumulating fat and enlarges in size. A point comes when liver no longer can take it and starts undergoing destruction. What is Fatty Liver? Whenever the fat accumulation in liver crosses 5% of liver weight it is known as fatty liver. Though in last century alcohol was believed to be the major cause of fatty liver, the diet and lifestyle is rapidly becoming the major cause of fatty liver now. The disease is known as non alcoholic fatty liver disease or NAFLD. Once it starts destroying liver it is called as steatohepatitis or NASH. Who is likely to have it? All ...

  Liver is the largest internal organ of our body and has more than 500 functions. Considering the significance of liver, we expect it to cause symptoms even with minimal injury. However, liver is quite resilient with tremendous regenerating capacity and hence, symptoms do not appear till very late. Even with ongoing liver damage, liver tries to cope up by not only enhancing the function of remaining liver but also be growth of the liver tissue. Based on the acuity of liver damage we can get symptoms. When the liver suffers from acute insult, there are symptoms seen frequently (as we see with routine viral hepatitis). However, if it is chronic or gradual long standing damage, there would be no symptoms. Symptoms only develop in such situation when liver failure begins. We divide symptoms and signs of liver damage in three subgroups   A)  Acute Hepatitis – The symptoms are known to every one of us. The most common cause is viral hepatitis A or E. Patients initially have lo...

Hepatitis B  is a global public health problem, with the highest number of hepatitis B virus (HBV) positive cases in  China  and  India . Since the majority are asymptomatic, the disease burden is under appreciated. It is a unique challenge to manage HBV infection in pregnant women, as can have consequences to both mother and newborn. About 12 studies in the Indian subcontinent have looked specifically at the prevalence of hepatitis B surface antigen (HBsAg) positivity in the pregnant women. The prevalence rate of HBsAg positivity in pregnant women varies from 1-9% in different parts of the country. All pregnant women should be tested for hepatitis B surface antigen (HBsAg) early in pregnancy. Pregnancy does not have a major effect on the liver disease in mothers with chronic hepatitis B, except in the context of cirrhosis but cirrhosis is relatively uncommon in young childbearing women with HBV infection. All hepatitis B positive women should be monitored clos...

There is a myth that because alcohol is banned in Gujarat, there is no  liver disease in Gujarat . Though, alcohol is one of the major reasons for liver failure, there are many other diseases which one needs to be aware of. The most common cause of  liver failure in India  is  Hepatitis B . The most common cause of liver cancer is Hepatitis B. Those who were born before 2002 need to check themselves for hepatitis B. vaccination is available and is now a part of national immunization schedule. Hepatitis B has no symptoms and the only way to diagnose is a simple blood test. If you have received blood transfusion in past, you have the risk of being exposed to  Hepatitis C . The diet in Gujarat is full of sugars and oils. With adaption of western sedentary lifestyle, obesity and diabetes is on the rise. With that fatty liver is also on the rise.  Fatty liver  can cause liver damage similar to that caused by alcohol. Fatty liver is worldwide becom...

The answer is yes and no. It indeed is a liver problem and it indicated that there is fat accumulated in your liver. However, it is not just a  liver problem  and it is one of the manifestations of a complete metabolic problem. Liver is a store house. Whatever we eat, the excess amount is converted to fat and is stored in the liver. If on a daily basis, we have a positive balance between calories we eat and calories we burn, the difference is converted to fat and stored in the liver. Over a period of time the fat accumulated to such a great extent that it starts damaging your liver cells and they start dying. This is the time when your liver function tests start becoming abnormal. If no corrective action is taken at that moment, the liver tries healing itself with abnormal fibrosis and eventually it becomes cirrhosis. Once cirrhosis happens, it is irreversible and can then lead to all complications like blood in vomit, blood in stools, abnormal behavior, fluid accumula...

Liver  as you all know it, is not only the second largest organ of the body after skin, but also a major organ for metabolizing. Whatever we eat goes to liver before reaching anywhere else in the body. The liver stores the excess energy as fat and condensed glucose known as glycogen. So whenever we eat excessively, the energy is stored in liver as fat. If we continue to do so for months and years together, the liver starts accumulating fat and enlarges in size. A point comes when liver no longer can take it and starts undergoing destruction. What is Fatty Liver? Whenever the fat accumulation in liver crosses 5% of liver weight it is known as fatty liver. Though in last century alcohol was believed to be the major cause of fatty liver, the diet and lifestyle is rapidly becoming the major cause of fatty liver now. The disease is known as non alcoholic fatty liver disease or NAFLD. Once it starts destroying liver it is called as steatohepatitis or NASH. Who is likely to ha...

Blood in stools is a common symptom. Many of the individuals face it once in a while. But if it is a recurrent symptom, Ulcerative colitis is a  disease  that needs to be ruled out. Intestine is divided into two main parts- small and large. Large intestine is the last one metre of the intestine which helps not only in forming stools but also storing it till the time we evacuate during our routine defecation. What is Ulcerative Colitis? It is a type of disease where the last part of our intestine gets damaged by our own immune cells and is a type of Inflammatory Bowel Disease or in common terms, IBD. The other types of IBD are Crohn’s Disease and Microscopic Colitis. In ulcerative colitis, the lining of the large intestine gets damaged and ulcerated. Once it gets ulcerated it starts oozing blood. Who is likely to have it? Ulcerative colitis is common among young individuals of both the sexes, though, no age is protected from it. The exact cause of ulcerative colitis...