Dr. Pathik Parikh Hepatologist and Liver Transplant Physician

Liver is a complex organ with more than 500 functions. Liver diseases are not just limited to alcohol. Over the last two decades, liver diseases besides alcohol have been considered as a cause for liver failure. The list below is just to name a few. Non-Alcoholic Fatty Liver Disease Alcoholic Fatty Liver disease Viral Hepatitis Metabolic liver disease Autoimmune hepatitis Drug induced liver injury Vascular liver disease Congenital liver disease Primary biliary cholangitis Primary sclerosing cholangitis Infectious liver disease Granulomatous liver disease Fatty Liver disease is the most common cause of liver disease in India and worldwide. Alcohol related liver disease is constant through these years while viral hepatitis thanks to good treatment availability is decreasing. These liver diseases can present as any of the following manner. Asymptomatic – Incidental finding on investigations Acute hepatitis with or without jaundice Acute Liver failure Chronic hepatitis Cirrhosis of liver A...

  "Understanding Drug-induced Liver Injury (DILI): Symptoms, Causes, and Treatment" is a clear and informative title that covers the essential aspects of DILI. Here's an outline of what each section might include: Symptoms of Drug-induced Liver Injury (DILI): Overview of common symptoms such as fatigue, jaundice (yellowing of the skin and eyes), abdominal pain, nausea, vomiting, and loss of appetite. Discussion on the variability of symptoms depending on the severity and type of liver injury caused by different drugs. Causes of Drug-induced Liver Injury (DILI): Explanation of how certain medications and drugs can lead to liver injury. Classification of DILI based on mechanisms, such as direct hepatotoxicity, idiosyncratic reactions, and immune-mediated responses. Risk Factors for Drug-induced Liver Injury (DILI) : Identification of factors that increase the likelihood of developing DILI, including specific drug characteristics, patient-related factors (e.g., age, genetics...

  Intermittent fasting (IF) has gained popularity in recent years as a potential strategy for managing various health conditions, including fatty liver disease. Fatty liver disease, also known as non-alcoholic fatty liver disease (NAFLD), is characterized by the accumulation of fat in the liver. It can range from simple fatty liver (steatosis) to a more severe condition called non-alcoholic steatohepatitis (NASH), which can lead to liver inflammation and scarring (fibrosis). There is some evidence to suggest that intermittent fasting may be beneficial for individuals with fatty liver disease, although more research is needed to fully understand its efficacy and safety. Here are some key points to consider: Weight Loss: Intermittent fasting may lead to weight loss, which is a primary goal in managing fatty liver disease. Losing excess weight can help reduce the fat buildup in the liver and improve liver function. Improved Insulin Sensitivity: Intermittent fasting may improve insuli...